Needle-free mesotherapy or Mezopeeling is a skin rejuvenation treatment option developed as an alternative to the traditional needle mesotherapy method. Needle-free mesotherapy offers a painless method to treat skin problems and rejuvenate the skin.

• Effective Mixture: The active mixture used in needle-free mesotherapy contains a specific combination of TCA (Tricarboxylic Acid) and H2O2. This mixture deeply affects the skin and stimulates fibroblast growth factors under the skin, promoting skin renewal.
• Skin Renewal: Needle-free mesotherapy targets skin renewal and rejuvenation. With this method, skin revitalization and strengthening are possible without causing damage to the skin.
• Collagen Production: Needle-free mesotherapy increases collagen production under the skin. This helps tighten the skin and treat skin problems. It also stimulates new collagen production, providing biological stimulation in skin cells.
• Painless and Comfortable: Unlike traditional needle mesotherapy, needle-free mesotherapy offers a painless and comfortable treatment option. The active mixture is applied under the skin without the use of needles, providing a more comfortable experience for patients.
• Application Areas: Needle-free mesotherapy can be used for various skin problems such as sagging, loosening, scars, stretch marks, and pigmentation treatment on the face, neck, chest, and décolletage areas.
• Combined Treatment: Needle-free mesotherapy can be combined with filler treatments or other skin rejuvenation therapies. This can achieve more powerful and synergistic effects.

Needle-free mesotherapy or Mezopeeling may be an ideal option, especially for patients with a fear of needles. It is an effective skincare method for those who want to treat skin problems and rejuvenate their skin. The improvement and rejuvenation effects on the skin increase over time after the application.

Needle-free mesotherapy uses needle-free systems to transport active ingredients under the skin. The most commonly used technologies are as follows:

• Electroporation:

  Electroporation creates temporary micro-pores in the skin cells through brief electrical stimuli, allowing active ingredients to penetrate into the cells. The electric field causes the phospholipid layers in the cell membrane to rearrange, increasing cell permeability. These micro-pores allow molecules to pass through the skin barrier.

• Ultrasonic Waves:

  Ultrasonic technology uses high-frequency sound waves to create temporary spaces between skin cells. These spaces allow larger molecules to reach deeper into the skin. Additionally, ultrasonic waves create a micro-massage effect on the skin, enhancing blood circulation and lymph drainage.

• Cavitation:

  Low-frequency ultrasound creates micro-bubbles on the skin surface. When these bubbles burst, they form microchannels that help active ingredients pass through the skin barrier.

Scientific studies on needle-free mesotherapy have shown that this method is highly effective in skincare. A study on electroporation techniques found that hyaluronic acid penetration could be increased by up to 30% compared to injection methods. Additionally, the lower risk of side effects with non-invasive methods is considered a significant advantage.

Clinical Findings:

After 4 to 6 sessions, significant improvements in skin hydration have been observed.

In cases of hyperpigmentation problems like melasma, a reduction in spot appearance by up to 40% has been reported.

Significant reduction in the depth of fine lines and wrinkles, and increased skin elasticity have been observed.

Advantages and Application Areas

• Painless and Comfortable: No pain is felt during the active ingredient delivery under the skin.
• No Infection Risk: Since no needles are used, the risk of infection is eliminated.
• Short Recovery Time: Immediate return to social life after treatment.
• Wide Range of Applications: Effective in many areas such as anti-aging treatments, spot treatments, skin tone balancing, and moisturizing.